Pilot Freeze Dryer

After the samples become freeze-dried preparations, they are more stable, especially for high temperature sensitive drugs, and most of them can be transported and stored at 0-4℃ or even normal temperature after freeze-dried, so the transportation and storage cost and inactivation risk are greatly reduced.

Compared with traditional drying methods, the bioactive materials can restore their pre-freeze-dried conformation and biological function after redissolution. Therefore, freeze-drying is the safest method with the least impact on the properties of the drying materials.

1. Is filling equipment available? – Yes.

2. Is gradient cooling possible? Precise multi-stage temperature control? -- Yes. You can set up freely on the program. In the meanwhile, Haier Biomedical owns a professional process design team who can support you improve your freeze drying process.

3.What’s the capacity for one batch?

Penicillin Ф12mm: Circa. 3690pcs;

Penicillin Ф16mm: Circa. 2046pcs;

Penicillin Ф22mm: Circa. 1056pcs

4. Is drying end point judgment possible? -- Yes, this is an optional function.

5. Is HDG-70Z10-50 able to monitor eutectic point? – Yes. We can supply a eutectic point detection device. In the meanwhile, our technical team can help you to find out!

1. Cascade dual system with Tecumseh compressors.

2. The hydraulic system includes hydraulic station, plate cylinder and other components, which are mainly used for shelf lifting movement and stopper.

3. Vacuum system includes rotary vane vacuum pump, electric evacuation valve and stainless-steel pipe road, chamber and cold trap are equipped with vacuum probe. The vacuum is controlled by the leak control valve, and the vacuum range is precisely controlled by PID regulation.

4. The circulating system includes circulating pump, heater, plate heat exchanger, expansion box and other components, and is connected through stainless steel tubes. Silicone oil (carrying refrigerant) transfers the heat and cold amount generated by the heater/plate heat exchanger to the shelf layer and products.

5. The control system is based on the PC-PLC double-layer structure independently developed in-house, and Siemens PLC is used to monitor equipment status, control equipment operation and execute related control chain. PC operation interface is available as well.

Product Features

Suitable for Small batch production & Pilot Run

Shelf total size: 0.54㎡ 

Capacity: Circa. 2,046 Penicillin bottles Ф16mm.

Excellent temperature Uniformity Control

±0.5℃ shelf temperature accuracy

±1℃ uniformity for all shelves

Superb Cooling Performance

Experience rapid cold trap pull down from+20°C to -45°C in just 30 minutes, with the ability to reach ultimate temperatures of -70°C

Achieve simultaneous cabinet and coldtrap cooling, reducing wait times and enhancing effciency


Sample Safety

Emergency protection function as standard

Complete Compliance documents

CE, FDA 21 CFR part 11, GMP, SAT, SAT, 3Q.

Specifications

Model Cold Trap Temperature (°C) Ice condenser capacity (kg) Power Supply (V/Hz) Weight (kg) Exterior Dimension (W*D*H)(mm) Shelf dimension (mm)
Pilot Freeze Dryer -80~-70 10 230/60 800 890*1660*1940 300*450

Resources

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Pilot Freeze Dryer HDG-70Z10-50
Shelves & Defrost
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Pilot Freeze Dryer Intro
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HDG-70Z10-50
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